International Psychogeriatrics
Volume 15, Supplement 1 - 2003
Monogenic Causes of Stroke MARTIN DICHGANS
ABSTRACT. Monogenic disorders account for only a minority of strokes. Yet, they have been
particularly helpful in exploring basic disease mechanisms. This article summarizes some recent
data on monogenic stroke while focusing on two conditions: CADASIL, as a genetic variant of
ischemic small vessel disease, and familial forms of cerebral amyloid angiopathy, which share
many properties with sporadic disease.
