International Psychogeriatrics
Volume 15, Supplement 1 - 2003
Functional Brain Imaging as a Surrogate Marker in Vascular Cognitive
Impairment ETSURO MORI
ABSTRACT. Functional brain imaging represents cerebrovascular status, neuronal status, and
neuronetwork status, and plays an increasingly important role in the evaluation of vascular
cognitive impairment or vascular dementia. In this article, the roles of functional brain
imaging are discussed in evaluation of subcortical lesions disrupting cortico-subcortical
circuits and in the study of white-matter changes in dementia. Also mentioned is an ongoing
clinical trial of extracranial-intracranial artery bypass surgery for hemispheric hemodynamic
misery perfusion where single-photon emission tomography is used as a surrogate measure.
